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Starting from cryptophane-A as a building block, we design different xenon biosensors. Their xenon NMR signal is very sensitive to the environment and can report different physico-chemical events. Such sensors change their resonance frequency, e.g.,  upon cellular internalization.
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Properties of the xenon host can be changed by attaching different functional units to implement binding to specific targets.
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Biosensor Engineering
Molecular Imaging
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