Contact
Dr. Leif Schröder
phone +49 30 94793 121
Leibniz-Institut für
Molekulare
Pharmakologie im Forschungsverbund
Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100
+4930 94793 – 109

Contact
Dr. Leif Schröder

phone +49 30 94793 121
🖂  lschroeder(at)fmp-berlin.de
Leibniz-
Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund
Berlin e.V. (FMP)

Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+49 30 94793 - 100
+49 30 94793 - 109 (Fax)
🖂
  info(at)fmp-berlin.de
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Xenon Hyperpolarization
Molecular Imaging
Methods
The production of hyperpolarized xenon is based on spin exchange optical pumping (SEOP) and is performed with our in-house developped LEIPNIX (Laser Enabled Increase of Polarization for Nuclei of Imprisoned Xenon) polarizer.
The D1 transition of rubidium vapor in a glass cell is pumped with a diode laser emitting at 795 nm. Together with a static magnetic field of ca. 20 G this allows to achieve a high electron spin polarization according to the selection rules. Xenon gas flowing through the pumping cell picks up this polarization through the Fermi contact interaction between the Rb electron and the Xe nucleus.
See also our following publications:
Physica Medica - Eur. J. Med. Phys. 29(1): 3-16 (2013); [
doi: 10.1016/j.ejmp.2011.11.001]
Chem. Eur. J. 23(4): 725-751 (2017) [doi: 10.1002/chem.201603884]
Chemistry, Molecular Sciences and Engineering, Encyclopedia of Analytical Science, Third Edition, 168–181 (2019) [doi: 10.1016/B978-0-12-409547-2.14072-7]